A penny for your method: AMPure substitute

NOTE:  This is a repost of an entry that I wrote for the molecularecologist.com. This week may stand as the most exciting week of the year for decreasing the cost of PCR cleanup, DNA cleanup, and library prep. Why, you ask? Because a great paper was published over in…

Dr. Prepper

NOTE:  This is a repost of an entry that I wrote for the molecularecologist.com. Library preparation for next-gen sequencing has become a fact of life in many labs working with model and non-model organisms. The problems with library preparation are that (1) library prep is slow and (2) library…

Easing the pain of titration

NOTE:  This is a repost of an entry that I wrote for the molecularecologist.com. Quickly following up on Nick's post re: Illumina Library Prep, Travis Glenn pointed me towards a manuscript in Nature Protocols that proposes an alternative to the oft-grumbled-about process of titrating libraries for 454/Ion Torrent…

A penny for your method: PCR cleanup

NOTE:  This is a repost of an entry that I wrote for the molecularecologist.com. Very rarely, in scientific research, do we get the opportunity to do less with more. As a result, one thing that we are good at is stretching a dollar. To (hopefully) contribute something back to…